Research
Clinical Research Trials for Gout
Gout has been documented for thousands of years, yet treatment options for have been slow to come. Thankfully, effective options for gout treatment are now available – and more are coming. Patient participation in clinical trials is crucial to increase the number of new and innovative treatment options for gout patients.
What is a clinical trial?
Clinical trials are research studies that evaluate the effectiveness of a medical treatment. Each clinical trial looks different, but they all advance through at least three primary phases to test a treatment, ensure its safety, and identify any side effects. If the drug or intervention is found to be safe and effective, the drug then undergoes an approval process through the U.S. Food and Drug Administration.
Gout clinical trials have led to the development of innovative treatments. Still, more potential medications are in clinical trials, which could lead to additional treatment options for patients.
Why should gout patients participate?
Clinical trials can transform research into medicines that improve the quality of life for gout patients. Participation can benefit both individual patients and society by offering:
- First-hand experience with new treatments.
- Effective treatment for patients who don’t respond to current medications.
- Hope for others who suffer from the same disease.
- Opportunities for one-on-one discussions with experts.
How to get involved
If you want to join a clinical trial, talk to your doctor to see if it’s the right option for you. You can explore current clinical trials at clinicaltrials.gov. Below, please find a list of GSGA partners and the clinical trials they are currently supporting.
| Name | Company Name | Study Enrolling Patients With: | Description | Additional Information |
| FORWARD OL | Horizon Therapeutics | Uncontrolled gout | Currently, in Phase 4 clinical trials, this study evaluates monthly infused dosing of KRYSTEXXA with methotrexate in patients with uncontrolled gout. | Clinicaltrials.gov |
| AGILE | Horizon Therapeutics | Uncontrolled gout | Currently, in Phase 4 clinical trials, this study evaluates the impact of administering KRYSTEXXA over a shorter infusion duration in patients with uncontrolled gout who are receiving methotrexate. | Clinicaltrials.gov |
| The EURELIA Research Study | LG Chem | Hyperuricemia and a history or presence of gout | Currently, in Phase 3 clinical trials, this study evaluates the efficacy and safety of three dosing levels of the oral medication TIGULIXOSTAT in gout patients over a 12-month period. | EURELIA Study Website |
Additional Resources:
Blogs
- Gout Clinical Trials: Perspective from Dr. Chris Parker
- Gary’s Story: Clinical Trials
- Ever Thought of Joining a Clinical Trial?
Documents
Facebook Live Event
- Gout & Clinical Trials – April 13, 2023
Have more questions? Read GSGA’s frequently asked questions on clinical trials: