The Gout and Chronic Kidney Disease Connection

Gout and chronic kidney disease – a vicious cycle where one tends to step on the other’s toes.

About one in ten people with chronic kidney disease also suffer from gout, and an even larger number of people with gout experience kidney disease.

The Connection

Gout can lead to kidney disease. Gout causes excess uric acid in the blood. This buildup can form urate crystals that damage the kidneys as they pass through and can lead to kidney disease.

Kidney disease can cause gout. The kidneys work to filter out waste – such as uric acid – from the body. But if you are living with chronic kidney disease, the kidneys are less effective in removing uric acid, causing a buildup that can lead to gout. Additionally, medication associated with chronic kidney disease, like diuretics and beta blockers, can also advance the severity of gout.

These interactions between gout and chronic kidney disease create a cycle that worsens both conditions.

Risk Factors

Understanding risk factors for gout and chronic kidney disease is important in identifying and managing these conditions. While gout affects more men, women’s risk rises after menopause.

Key risk factors for gout include:

  • Genetics
  • Age
  • Weight

Key risk factors for chronic kidney disease include:

  • Genetics
  • Diabetes
  • Hypertension

Managing Gout with Kidney Disease

Managing gout if you have kidney disease requires addressing unique challenges.

  • Regular monitoring of uric acid levels can enable early detection and prevention.
  • Medications focused on lowering uric acid levels offer an effective means of managing gout. Patients with kidney disease should talk to their doctor about what medications are safe for gout and kidney disease.
  • Lifestyle adjustments, such as maintaining a healthy weight and staying hydrated, can also play a role in management.

Understanding the gout and chronic kidney disease connection is the first step in identifying your symptoms and managing both conditions with your doctor.